Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman
- PMID: 18211621
- DOI: 10.1111/j.1365-2710.2008.00881.x
Neutropenia, thrombocytopenia and hepatic injury associated with dexketoprofen trometamol therapy in a previously healthy 35-year-old woman
Abstract
This case report describes a previously healthy 35-year-old woman, with an episode of fever, neutropenia, thrombocytopenia and elevation of biochemical markers of liver injury, 10 days after beginning drug therapy with dexketoprofen trometamol. Infectious and autoimmune causes of neutropenia, and viral or autoimmune hepatitis were excluded. The resolution following withdrawal of dexketoprofen trometamol confirms the possibility of an adverse drug reaction.
Similar articles
-
Single and repeated dose pharmacokinetics of dexketoprofen trometamol in patients with impaired liver function.Methods Find Exp Clin Pharmacol. 2006 Jun;28 Suppl A:29-36. Methods Find Exp Clin Pharmacol. 2006. PMID: 16801990 Clinical Trial.
-
Postmarketing cohort study to assess the safety profile of oral dexketoprofen trometamol for mild to moderate acute pain treatment in primary care.Methods Find Exp Clin Pharmacol. 2009 Oct;31(8):533-40. doi: 10.1358/mf.2009.31.8.1419070. Methods Find Exp Clin Pharmacol. 2009. PMID: 19967102
-
Photoallergic contact dermatitis from dexketoprofen: study of 6 cases.Contact Dermatitis. 2006 Jul;55(1):59-61. doi: 10.1111/j.0105-1873.2006.0847g.x. Contact Dermatitis. 2006. PMID: 16842562 No abstract available.
-
Dexketoprofen trometamol: clinical evidence supporting its role as a painkiller.Expert Rev Neurother. 2008 Nov;8(11):1625-40. doi: 10.1586/14737175.8.11.1625. Expert Rev Neurother. 2008. PMID: 18986233 Review.
-
Chiral non-steroidal anti-inflammatory drugs--a review.J Indian Med Assoc. 2008 Sep;106(9):615-8, 622, 624. J Indian Med Assoc. 2008. PMID: 19552094 Review.
Cited by
-
Esophagitis due to dexketoprofen trometamol: a rare case report.Wien Klin Wochenschr. 2015 May;127(9-10):399-401. doi: 10.1007/s00508-014-0658-6. Epub 2014 Nov 21. Wien Klin Wochenschr. 2015. PMID: 25412595
-
Practical guidelines for diagnosis and early management of drug-induced liver injury.World J Gastroenterol. 2008 Nov 28;14(44):6774-85. doi: 10.3748/wjg.14.6774. World J Gastroenterol. 2008. PMID: 19058303 Free PMC article. Review.
-
Anaphylaxis after intravenous infusion of dexketoprofen trometamol.Turk J Emerg Med. 2016 Sep 29;16(3):132-133. doi: 10.1016/j.tjem.2016.09.003. eCollection 2016 Sep. Turk J Emerg Med. 2016. PMID: 27857995 Free PMC article.
-
Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study.Med Oral Patol Oral Cir Bucal. 2014 Nov 1;19(6):e622-7. doi: 10.4317/medoral.19835. Med Oral Patol Oral Cir Bucal. 2014. PMID: 25129247 Free PMC article. Clinical Trial.
-
Oxytocin and cardioprotection in diabetes and obesity.BMC Endocr Disord. 2016 Jun 7;16(1):34. doi: 10.1186/s12902-016-0110-1. BMC Endocr Disord. 2016. PMID: 27268060 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources