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Review
. 1991 Jul;2(3):565-8.

Agenesis of the corpus callosum. Its associated anomalies and syndromes with special reference to the Apert syndrome

M M Cohen Jr  1 , S Kreiborg
Affiliations
  • PMID: 1821304
Review

Agenesis of the corpus callosum. Its associated anomalies and syndromes with special reference to the Apert syndrome

M M Cohen Jr et al. Neurosurg Clin N Am. 1991 Jul.

Abstract

Agenesis of the corpus callosum may be associated with a variety of central nervous system (CNS) and non-CNS abnormalities and is known to occur in a number of specific syndromes. It can be a marker for several inherited metabolic disorders. Study of the Apert syndrome shows a recurrent pattern of CNS abnormalities, including defects of the corpus callosum and limbic structures, megalencephaly, misshapen brain, distortion ventriculomegaly, and gyral anomalies.

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