MicroParticle photophysics illuminates viral bio-sensing
- PMID: 18214098
- DOI: 10.1039/b702920a
MicroParticle photophysics illuminates viral bio-sensing
Abstract
The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere-based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.
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