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Case Reports
. 2007 Jul;13(7):1094-6.
doi: 10.3201/eid1307.070063.

Possible zoonotic transmission of hepatitis E from pet pig to its owner

Christophe Renou  1 , Jean-Francois Cadranel, Marc Bourlière, Philippe Halfon, Denis Ouzan, Hervè Rifflet, Philippe Carenco, Abdelouahid Harafa, Jean Jacques Bertrand, Annie Boutrouille, Pierre Muller, Jean-Pierre Igual, Anne Decoppet, Marc Eloit, Nicole Pavio
Affiliations
Case Reports

Possible zoonotic transmission of hepatitis E from pet pig to its owner

Christophe Renou et al. Emerg Infect Dis. 2007 Jul.

Abstract

Hepatitis E is transmitted mainly by water or food, but in industrialized countries, all routes of transmission have not been identified. We describe possible zoonotic transmission of hepatitis E virus that involved direct contact between a pet pig and its owner.

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Figures

Figure 1
Figure 1
Phylogenetic tree (neighbor-joining method) of hepatitis E virus (HEV) genotype 3 isolates for a 210-nt sequence within the open reading frame (ORF) 1 gene (corresponding to nt 167–376 of the prototype swine genotype 3 pSHEV-3 AY575859). Patient (EF514587) and pet pig (EF514588) sequences are in boldface and were compared with French isolates or known isolates from regions where HEV is not endemic. GenBank accession no. and country of origin are indicated. Reliability of the different phylogenetic groupings was evaluated by using a bootstrap test (1,000 replications); scores >70% are indicated. Scale bar indicates no. of nucleotide substitutions per site. JP, Japan; USA, United States; NL, the Netherlands; NZ, New Zealand; IT, Italy; FR, France; AR, Argentina; UK, United Kingdom; SP, Spain.
Figure 2
Figure 2
Phylogenetic tree (neighbor-joining method) of hepatitis E virus (HEV) genotype 3 isolates for a 273-nt sequence within the open reading frame 2 gene (corresponding to nt 6078–6350 of the prototype swine genotype 3 pSHEV-3 AY 575859). Patient (EF050798) and pet pig (EF050797) sequences are in boldface and were compared with French isolates or known isolates from regions where HEV is not endemic. GenBank accession no. and country of origin are indicated. Reliability of the different phylogenetic grouping was evaluated by using a bootstrap test (1,000 replications); scores >70% are indicated. Scale bar indicates no. of nucleotide substitutions per site. SP, Spain; FR, France; NL, the Netherlands; JP, Japan; USA, United States; UK, United Kingdom.
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References

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