Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- PMID: 18216293
- PMCID: PMC2972576
- DOI: 10.1182/blood-2007-06-093906
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
Erratum in
- Blood. 2008 Dec 15;112(13):5259
Abstract
Standardized criteria for diagnosis and response assessment are needed to interpret and compare clinical trials and for approval of new therapeutic agents by regulatory agencies. Therefore, a National Cancer Institute-sponsored Working Group (NCI-WG) on chronic lymphocytic leukemia (CLL) published guidelines for the design and conduct of clinical trials for patients with CLL in 1988, which were updated in 1996. During the past decade, considerable progress has been achieved in defining new prognostic markers, diagnostic parameters, and treatment options. This prompted the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) to provide updated recommendations for the management of CLL in clinical trials and general practice.
Comment in
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The proposed diagnostic criteria change for chronic lymphocytic leukemia: unintended consequences?Blood. 2009 Jun 18;113(25):6495-6. doi: 10.1182/blood-2008-05-158444. Blood. 2009. PMID: 19541837 No abstract available.
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Lymphocytes, B lymphocytes, and clonal CLL cells: observations on the impact of the new diagnostic criteria in the 2008 Guidelines for Chronic Lymphocytic Leukemia (CLL).Blood. 2009 Jun 18;113(25):6496-7; author reply 6497-8. doi: 10.1182/blood-2008-07-166710. Blood. 2009. PMID: 19541838 No abstract available.
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Clearly defined response criteria evaluating treatment of CLL patients in clinical research trials.Blood. 2010 Sep 9;116(10):1817; author reply 1817-8. doi: 10.1182/blood-2010-03-274035. Blood. 2010. PMID: 20829381 No abstract available.
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Microvesicles in chronic lymphocytic leukemia: ready for prime time in the clinic?Leuk Lymphoma. 2017 Jun;58(6):1281-1282. doi: 10.1080/10428194.2017.1298756. Leuk Lymphoma. 2017. PMID: 28271951 No abstract available.
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