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Case Reports
. 2007 Nov;13(11):1647-52.
doi: 10.3201/eid1311.070665.

Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients

Pierre Loulergue  1 , Frédéric Bastides, Véronique Baudouin, Jacques Chandenier, Patricia Mariani-Kurkdjian, Bertrand Dupont, Jean-Paul Viard, Françoise Dromer, Olivier Lortholary
Affiliations
Case Reports

Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients

Pierre Loulergue et al. Emerg Infect Dis. 2007 Nov.

Abstract

African histoplasmosis caused by Histoplasma capsulatum var. duboisii is an invasive fungal infection endemic in central and west Africa. Most of its ecology and pathogenesis remain unknown. H. capsulatum var. capsulatum is an AIDS-defining opportunistic infection in HIV-infected patients who are living in or have traveled to histoplasmosis-endemic areas. In contrast, reports concerning African histoplasmosis during HIV infection are rare, although both pathogens coexist in those regions. We report 3 cases of imported African histoplasmosis diagnosed in France in HIV-infected patients and a literature review on similar cases.

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Figures

Figure 1
Figure 1
Direct examination of bone marrow smear. Intracytoplasmic Histoplasma capsulatum var. capsulatum.
Figure 2
Figure 2
Direct examination of sputum fluid showing Histoplasma capsulatum var. duboisii.
See this image and copyright information in PMC

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