Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU
- PMID: 18219516
- DOI: 10.1007/s11845-008-0115-5
Critically ill newborns with multiple organ dysfunction: assessment by NEOMOD score in a tertiary NICU
Abstract
Background: The neonatal multiple organ dysfunction score (NEOMOD) predicts mortality during the first 28 days of life, and provides information on organ functions influencing mortality.
Aim: To test the predictive and descriptive accuracy of NEOMOD in very low birth weight (VLBW) infants.
Methods: The system was used in 112 infants. It evaluates the central nervous system (CNS), coagulation, respiratory, gastrointestinal (GIT), cardiovascular (CVS), renal system, and acid-base balance in 24-h intervals during the first 28 days of life.
Results: A NEOMOD of > or =9 was associated with 100% mortality. A receiver operating characteristic (ROC) curve was used for assessing the accuracy of NEOMOD score in prediction of mortality. The area under curve (AUC) attained by NEOMOD was 0.93 for mortality.
Conclusions: The NEOMOD evaluates daily the severity of the multiple organ dysfunction syndrome (MODS) and is an accurate predictor of mortality.
Similar articles
-
Characterization of multiple organ dysfunction syndrome in very low birthweight infants: a new sequential scoring system.Shock. 2001 May;15(5):348-52. doi: 10.1097/00024382-200115050-00003. Shock. 2001. PMID: 11336193
-
A new scoring system for evaluation of multiple organ dysfunction syndrome in premature infants.Am J Crit Care. 2012 Sep;21(5):328-37. doi: 10.4037/ajcc2012312. Am J Crit Care. 2012. PMID: 22941706
-
[New Apgar score? A multi-centre study dealing with the evaluation of the neonate NEOMOD scoring system for the first day of life].Ceska Gynekol. 2004 Dec;69 Suppl 1:85-90. Ceska Gynekol. 2004. PMID: 15748032 Czech.
-
Severity of illness and organ dysfunction scoring in children.Pediatr Crit Care Med. 2005 May;6(3 Suppl):S126-34. doi: 10.1097/01.PCC.0000161287.61028.D4. Pediatr Crit Care Med. 2005. PMID: 15857545 Review.
-
Epidemiology of multiple organ dysfunction syndrome in critical surgical illness.Surg Infect (Larchmt). 2000 Fall;1(3):173-85; discussion 185-6. doi: 10.1089/109629600750018105. Surg Infect (Larchmt). 2000. PMID: 12594888 Review.
Cited by
-
Pediatric palliative care in neonates: a cross-sectional study from a high-complexity hospital in Latin America. Neopalped study.BMC Palliat Care. 2025 May 22;24(1):141. doi: 10.1186/s12904-025-01753-y. BMC Palliat Care. 2025. PMID: 40405201 Free PMC article.
-
Differences in organ dysfunctions between neonates and older children: a prospective, observational, multicenter study.Crit Care. 2010;14(6):R202. doi: 10.1186/cc9323. Epub 2010 Nov 9. Crit Care. 2010. PMID: 21062434 Free PMC article.
-
Comparative Performance of Four Established Neonatal Disease Scoring Systems in Predicting In-Hospital Mortality and the Potential Role of Thromboelastometry.Diagnostics (Basel). 2021 Oct 21;11(11):1955. doi: 10.3390/diagnostics11111955. Diagnostics (Basel). 2021. PMID: 34829302 Free PMC article.
-
Interrelation between miRNAs Expression Associated with Redox State Fluctuations, Immune and Inflammatory Response Activation, and Neonatal Outcomes in Complicated Pregnancy, Accompanied by Placental Insufficiency.Antioxidants (Basel). 2022 Dec 21;12(1):6. doi: 10.3390/antiox12010006. Antioxidants (Basel). 2022. PMID: 36670868 Free PMC article.
-
Modified NEOMOD score as a neonatal mortality prediction tool in a medium-income country: A validation diagnostic test study.Health Sci Rep. 2023 May 17;6(5):e1065. doi: 10.1002/hsr2.1065. eCollection 2023 May. Health Sci Rep. 2023. PMID: 37205933 Free PMC article.
References
MeSH terms
LinkOut - more resources
Full Text Sources