Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Dec;7(12):1186-205.
doi: 10.2174/138955707782795647.

Combretastatin a-4 analogs as anticancer agents

Anurag Chaudhary  1 , S N Pandeya, P Kumar, P P Sharma, S Gupta, N Soni, K K Verma, G Bhardwaj
Affiliations
Review

Combretastatin a-4 analogs as anticancer agents

Anurag Chaudhary et al. Mini Rev Med Chem. 2007 Dec.

Abstract

Combretastatin A-4 (CA-4) is one of the most potent antimitotic and antiangiogenic agents of natural origin. It has displayed potent antitumor effect in a wide variety of preclinical tumor models. Till date various CA-4 analogs have been synthesized and evaluated for anticancer activity. This review is an attempt to compile the medicinal chemistry of various synthesized CA-4 analogs.

PubMed Disclaimer

LinkOut - more resources