Review
doi: 10.1111/j.1751-1097.2007.00276.x.
Epub 2008 Jan 23.
Photodynamic therapy in the treatment of actinic keratosis
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- PMID: 18221454
- DOI: 10.1111/j.1751-1097.2007.00276.x
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Review
Photodynamic therapy in the treatment of actinic keratosis
Photochem Photobiol.
2008 Mar-Apr.
Abstract
The efficacy of photodynamic therapy (PDT) with 5-aminolevulinate and methyl aminolevulinate in the treatment of actinic keratosis has been demonstrated in a large number of clinical studies over the last several years. Here, we recapitulate the major findings, comparing the various photosensitizers, light sources and therapeutic regimens, and present a retrospective analysis of 142 own cases treated with 259 PDTs. In addition, we also discuss the value of PDT in comparison with cryotherapy or 5-fluorouracil. The efficacy and the low risk of side effects of PDT have resulted in a high patient preference in clinical trials.
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