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Review
. 1991 Dec;1(4):538-43.
doi: 10.1016/s0959-437x(05)80205-9.

Telomeres--what's new at the end?

E R Henderson  1 , D D Larson
Affiliations
Review

Telomeres--what's new at the end?

E R Henderson et al. Curr Opin Genet Dev. 1991 Dec.

Abstract

Telomeres are specialized chromatin domains located at the ends of chromosomes. They are involved in chromosome replication, stability and localization in the nucleus. In addition to these functions, recent work suggests that telomeres are involved in such superficially diverse cellular phenomena as ageing, cancer, nuclear architecture and nuclear/cellular division.

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