Available biological treatments for complex non-unions
- PMID: 18224732
- DOI: 10.1016/s0020-1383(08)70004-4
Available biological treatments for complex non-unions
Abstract
The treatment of complex non-unions may be lengthy and very expensive. The majority of aseptic non-union cases require a variable degree of biological enhancement. Autologous iliac crest bone graft remains the gold standard of treatment. However, other means of biological stimulation are currently available in the armamentarium of the treating physician. This review article reports on the different available biological treatment options for the management of complex aseptic bone non-unions.
Similar articles
-
Treatment of long bone non-unions with polytherapy: indications and clinical results.Injury. 2011 Jun;42(6):587-90. doi: 10.1016/j.injury.2011.03.046. Epub 2011 Apr 27. Injury. 2011. PMID: 21524745 Review.
-
Biological enhancement of tibial diaphyseal aseptic non-unions: the efficacy of autologous bone grafting, BMPs and reaming by-products.Injury. 2007 May;38 Suppl 2:S65-75. doi: 10.1016/s0020-1383(07)80011-8. Injury. 2007. PMID: 17920420 Review.
-
Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions?Injury. 2007 Mar;38 Suppl 1:S75-80. doi: 10.1016/j.injury.2007.02.012. Injury. 2007. PMID: 17383488 Review.
-
Clinical and Research Approaches to Treat Non-union Fracture.Curr Osteoporos Rep. 2018 Apr;16(2):155-168. doi: 10.1007/s11914-018-0432-1. Curr Osteoporos Rep. 2018. PMID: 29536393 Review.
-
Plate fixation of ununited humeral shaft fractures: effect of type of bone graft on healing.J Bone Joint Surg Am. 2006 Jul;88(7):1442-7. doi: 10.2106/JBJS.E.00332. J Bone Joint Surg Am. 2006. PMID: 16818968
Cited by
-
Teriparatide in Fracture Non-Unions.Transl Med UniSa. 2014 Sep 1;12:47-53. eCollection 2015 May-Aug. Transl Med UniSa. 2014. PMID: 26535187 Free PMC article.
-
Teriparatide, a nonsurgical solution for femoral nonunion? A report of three cases.Osteoporos Int. 2012 Dec;23(12):2897-900. doi: 10.1007/s00198-012-2172-x. Epub 2012 Oct 18. Osteoporos Int. 2012. PMID: 23076681
-
MC3T3-E1 osteoprogenitor cells systemically migrate to a bone defect and enhance bone healing.Tissue Eng Part A. 2012 May;18(9-10):968-73. doi: 10.1089/ten.TEA.2011.0545. Epub 2012 Jan 4. Tissue Eng Part A. 2012. PMID: 22129134 Free PMC article.
-
Long-term safety and efficacy of human bone morphogenetic protein (HBMP) in the treatment of resistant non-unions and failed arthrodesis.J Clin Orthop Trauma. 2017 Jan-Mar;8(1):59-62. doi: 10.1016/j.jcot.2016.10.008. Epub 2016 Nov 16. J Clin Orthop Trauma. 2017. PMID: 28360499 Free PMC article.
-
Gene expression dynamics during bone healing and osseointegration.J Periodontol. 2011 Jul;82(7):1007-17. doi: 10.1902/jop.2010.100577. Epub 2010 Dec 13. J Periodontol. 2011. PMID: 21142982 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources