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Comment
. 2008 Feb;11(2):123-4.
doi: 10.1038/nn0208-123.

Sleep: hitting the reset button

Comment

Sleep: hitting the reset button

Leslie C Griffith et al. Nat Neurosci. 2008 Feb.

Abstract

Many aspects of sleep, including the how and why, are still mysterious, especially its relationship to learning and memory. A new study suggests that sleep may serve to reset synaptic potentiation, linking it to homeostatic plasticity.

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Figures

Figure 1
Figure 1
The sleep state may provide an opportunity to reset synapses in the brain, depotentiating them back to baseline Awake episode is possible.

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References

    1. Vyazovskiy VV, Cirelli C, Pfister-Genskow M, Faraguna U, Tononi G. Nat Neurosci. 2008;11:200–208. - PubMed
    1. Blanco-Centurion C, et al. J Neurosci. 2006;26:8092–8100. - PMC - PubMed
    1. Stickgold R, Walker MP. Sleep Med. 2007;8:331–343. - PMC - PubMed
    1. Korman M, et al. Nat Neurosci. 2007;10:1206–1213. - PubMed
    1. Huber R, Ghilardi MF, Massimini M, Tononi G. Nature. 2004;430:78–81. - PubMed