Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2008 Jan 29;5(1):e25.
doi: 10.1371/journal.pmed.0050025.

New insights into impaired muscle glycogen synthesis

Affiliations
Comment

New insights into impaired muscle glycogen synthesis

Leif Groop et al. PLoS Med. .

Abstract

The authors discuss a new study showing that carriers of the mutation PPP1R3A show decreased muscle glycogen levels.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Comment on

References

    1. Groop L, Orho M. Metabolic aspects of glycogen synthase activation. In: Belfiore F, Lorenzi M, Molinatti GM, Porta M, . Molecular and cell biology of type 2 diabetes and its complications. Volume 14. Basel (Switzerland): Karger; 1998. pp. 47–55. In. editors.
    1. Eriksson J, Franssila-Kallunki A, Ekstrand A, Saloranta C, Widén E, et al. Early metabolic defects in persons at increased risk for non-insulin-dependent diabetes mellitus. New Engl J Med. 1989;321:337–343. - PubMed
    1. Shulman G, Rothman DL, Jue T, Stein P, DeFronzo RA, et al. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med. 1990;322:223–228. - PubMed
    1. Schalin-Jäntti C, Härkönen M, Groop LC. Impaired activation of glycogen synthase in people at increased risk for developing NIDDM (non-insulin-dependent diabetes mellitus) Diabetes. 1992;41:598–604. - PubMed
    1. Groop LC, Kankuri M, Schalin-Jäntti C, Ekstrand A, Nikula-Ijäs P, et al. Association between polypmorhism of glycogen synthase gene and non-insulin dependent diabetes. New Engl J Med. 1999;328:11–14. - PubMed

MeSH terms