Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Apr;46(4):1494-7.
doi: 10.1128/JCM.01945-07. Epub 2008 Jan 30.

Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals

Brian Louie  1 , Ernest Wong, Jeffrey D Klausner, Sally Liska, Frederick Hecht, Terri Dowling, Martha Obeso, Susan S Phillips, Mark W Pandori
Affiliations

Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals

Brian Louie et al. J Clin Microbiol. 2008 Apr.

Abstract

We have evaluated four current Food and Drug Administration-cleared rapid tests for human immunodeficiency virus (HIV)-specific antibodies with a panel of specimens from recently infected individuals. Recent infection was detected by RNA-based screening coupled with enzyme immunoassay-based testing. We found that the sensitivities of the various rapid tests vary greatly with regard to their ability to detect HIV-specific antibodies in recently infected individuals.

PubMed Disclaimer

References

    1. Anonymous. 2006. Rapid HIV test kits. Health Dev. 35157-177. - PubMed
    1. Constantine, N. T., G. van der Groen, E. Belsey, and H. Tamashiro. 1994. Sensitivity of HIV antibody assays as determined by seroconversion panels. AIDS 81715-1720. - PubMed
    1. Fiebig, E. W., D. J. Wright, B. D. Rawal, P. E. Garrett, R. T. Schumacher, L. Peddada, C. Heldebrandt, R. Smith, A. Conrad, S. H. Kleinman, and M. P. Busch. 2003. Dynamics of HIV viremia and antibody seroconversion in plasma donors: implications for diagnosis and staging of primary HIV infection. AIDS 171871-1879. - PubMed
    1. Fiscus, S. A., C. D. Pilcher, W. C. Miller, K. A. Powers, I. F. Hoffman, M. Price, D. A. Chilongozi, C. Mapanje, R. Krysiak, S. Gama, F. E. Martinson, M. S. Cohen, and the Malawi-University of North Caronlina Project Acute HIV Infection Study Team. 2007. Rapid, real-time detection of acute HIV infection in patients in Africa. J. Infect. Dis. 195416-424. - PubMed
    1. Franco-Paredes, C., I. Tellez, and C. del Rio. 2006. Rapid HIV testing: a review of the literature and implications for the clinician. Curr. HIV/AIDS Rep. 3169-175. - PubMed

Publication types