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Review
. 2008 Jan-Feb;14(1):112-24.
doi: 10.4158/EP.14.1.112.

Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events?

David S H Bell  1 , James H O'Keefe, Paul Jellinger
Affiliations
Review

Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events?

David S H Bell et al. Endocr Pract. 2008 Jan-Feb.

Abstract

Objective: To investigate the association of postprandial dysmetabolism, ie, hyperglycemia, and hyperlipidemia with myocardial disease in diabetic, glucose-intolerant, and glucose-tolerant patients.

Methods: We performed a MEDLINE search of the English-language literature published between January 1979 and April 2007 for studies regarding postprandial dysmetabolism and heart disease.

Results: Postprandial dysmetabolism is associated with increased inflammation, endothelial dysfunction, decreased fibrinolysis, plaque instability, and cardiac events.

Conclusion: There is a direct and proportional association between postprandial dysmetabolism and both coronary artery disease and cardiac events.

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