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Review
. 2008 Feb;31(2):416-69.
doi: 10.1183/09031936.00099306.

Outcomes for COPD pharmacological trials: from lung function to biomarkers

M Cazzola  1 , W MacNee, F J Martinez, K F Rabe, L G Franciosi, P J Barnes, V Brusasco, P S Burge, P M A Calverley, B R Celli, P W Jones, D A Mahler, B Make, M Miravitlles, C P Page, P Palange, D Parr, M Pistolesi, S I Rennard, M P Rutten-van Mölken, R Stockley, S D Sullivan, J A Wedzicha, E F Wouters; American Thoracic Society; European Respiratory Society Task Force on outcomes of COPD
Affiliations
Free article
Review

Outcomes for COPD pharmacological trials: from lung function to biomarkers

M Cazzola et al. Eur Respir J. 2008 Feb.
Free article

Abstract

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.

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