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. 1976 May 31;282(21):1893-6.

[Possible role of cell contact in the control of a differentiation program in Dictyostelium discoideum]

[Article in French]
  • PMID: 182409

[Possible role of cell contact in the control of a differentiation program in Dictyostelium discoideum]

[Article in French]
M M Darmon. C R Acad Hebd Seances Acad Sci D. .

Abstract

Synthesis of cAMP-phosphodiesterase falls at the end of the aggregation phase in Dictyostelium discoideum. Exogenous cAMP pulses, known to induce they synthesis of that enzyme during the course of the aggregation process, do not prevent the shut off of enzyme synthesis. Specific intercellular contacts which form at the end of aggregation seem to be required for the inhibition of enzyme synthesis.

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