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. 2008 May;117(5):337-41.
doi: 10.1111/j.1600-0447.2008.01154.x. Epub 2008 Jan 30.

Insulin resistance and lipid levels in adolescents with familial risk for psychosis

H Koponen  1 , P Mäki, H Halonen, J Miettunen, J Laitinen, T Tammelin, I Moilanen, A Taanila, A Ruokonen, J Korkeila, J Veijola
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Insulin resistance and lipid levels in adolescents with familial risk for psychosis

H Koponen et al. Acta Psychiatr Scand. 2008 May.

Abstract

Objective: Type 2 diabetes and dyslipidemias co-occur frequently with schizophrenia. It is not known how common they are in adolescents with a familial risk for psychosis.

Method: The Northern Finland 1986 Birth Cohort consists of 9432 children born alive in the two Northernmost provinces in Finland. At the age of 15/16 they participated in clinical examination including measurements of glucose, lipids and IR, and a questionnaire including items about their diet and physical activity. The Finnish Hospital Discharge Register was used to find out non-organic psychoses in parents during 1972-2000. This familial risk was found out in 54 boys and 68 girls. Their results were compared with other cohort members.

Results: No differences were observed in the cardiometabolic risk factors between the study groups.

Conclusion: Our results suggest that familial risk for psychosis is not directly associated with disturbances of glucose and lipid metabolism among adolescents.

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