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Review
. 2008 Feb;55(1):71-96, x.
doi: 10.1016/j.pcl.2007.10.013.

Indications and donor selections for allogeneic stem cell transplantation in children with hematologic malignancies

Rupert Handgretinger  1 , Joanne Kurtzberg, R Maarten Egeler
Affiliations
Review

Indications and donor selections for allogeneic stem cell transplantation in children with hematologic malignancies

Rupert Handgretinger et al. Pediatr Clin North Am. 2008 Feb.

Abstract

Allogeneic stem cell transplantation (SCT) is the only curative approach for many patients with advanced or high-risk leukemia. Advances in supportive care and management of graft-versus-host disease have resulted in improvements in outcomes of related and unrelated donor SCT, creating controversies as to which strategy might be the optimal therapy for individual patients. This article discusses the indications and donor selection strategies for SCT in patients with malignant hematologic disease.

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