Facultative endocrine progenitor cells in the adult pancreas
- PMID: 18243094
- DOI: 10.1016/j.cell.2008.01.004
Facultative endocrine progenitor cells in the adult pancreas
Abstract
Using a unique injury model of the pancreas in mouse, Xu et al. (2008) now reveal the involvement of neurogenin3, a marker for embryonic-type endocrine progenitor cells, in the formation of new insulin-producing beta cells. These neurogenin3-positive facultative endocrine progenitor cells in the adult pancreas may be of potential value for treating diabetes.
Comment on
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.Cell. 2008 Jan 25;132(2):197-207. doi: 10.1016/j.cell.2007.12.015. Cell. 2008. PMID: 18243096
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical