A very private TGF-beta receptor embrace
- PMID: 18243107
- DOI: 10.1016/j.molcel.2008.01.006
A very private TGF-beta receptor embrace
Abstract
In this issue of Molecular Cell, Groppe et al. (2008) describe the crystal structure of a six-element TGF-beta:receptor complex, addressing long-standing questions about the restrictive nature of this vital receptor interaction.
Comment on
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Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding.Mol Cell. 2008 Feb 1;29(2):157-68. doi: 10.1016/j.molcel.2007.11.039. Mol Cell. 2008. PMID: 18243111
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