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. 2008 Nov;43(11):2473-8.
doi: 10.1016/j.ejmech.2007.12.014. Epub 2007 Dec 27.

Chemotherapy of leishmaniasis part-VIII: synthesis and bioevaluation of novel chalcones

S N Suryawanshi  1 , Naveen Chandra, Pawan Kumar, Jyoti Porwal, Suman Gupta
Affiliations

Chemotherapy of leishmaniasis part-VIII: synthesis and bioevaluation of novel chalcones

S N Suryawanshi et al. Eur J Med Chem. 2008 Nov.

Abstract

Some novel dihydro-alpha-ionone based chalcones have been synthesized and evaluated for their in vitro antileishmanial activity in promastigote and amastigote model. Some of the compounds showed 100% inhibition at 5 and 2 microm/ml concentration.

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