Judah Folkman, a pioneer in the study of angiogenesis
- PMID: 18247146
- PMCID: PMC2268723
- DOI: 10.1007/s10456-008-9092-6
Judah Folkman, a pioneer in the study of angiogenesis
Abstract
More than 30 years ago, Judah Folkman found a revolutionary new way to think about cancer. He postulated that in order to survive and grow, tumors require blood vessels, and that by cutting off that blood supply, a cancer could be starved into remission. What began as a revolutionary approach to cancer has evolved into one of the most exciting areas of scientific inquiry today. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.
References
-
- None
- Ide AG, Baker NH, Warren SL (1939) Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber. AJR 32:891–899
-
- None
- Algire GH, Chalkley HW (1945) Vascular reactions of normal and malignant tissue in vivo. J Natl Cancer Inst 6:73–85
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '13346338', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/13346338/'}]}
- Melwin RM, Algire GH (1956) The role of graft and host vessels in vascularization of grafts of normal and neoplastic tissues. J Natl Cancer Inst 17:23–33 - PubMed
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '5662020', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/5662020/'}]}
- Greenblatt M, Shubik P (1968) Tumor angiogenesis: transfilter diffusion studied in the hamster by the transparent chamber technique. J Natl Cancer Inst 41:1111–1124 - PubMed
-
- {'text': '', 'ref_index': 1, 'ids': [{'type': 'PubMed', 'value': '5750121', 'is_inner': True, 'url': 'https://pubmed.ncbi.nlm.nih.gov/5750121/'}]}
- Ehrman RL, Knoth M (1968) Choriocarcinoma: transfilter stimulation of vasoproliferation in the hamster cheek pouch studied by light and electron microscopy. J Natl Cancer Inst 41:1329–1341 - PubMed
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