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Review
. 2008 Feb;7(2):97-8.
doi: 10.1016/j.cmet.2008.01.003.

Fighting fat with muscle: bulking up to slim down

Brooke C Harrison  1 , Leslie A Leinwand
Affiliations
Free article
Review

Fighting fat with muscle: bulking up to slim down

Brooke C Harrison et al. Cell Metab. 2008 Feb.
Free article

Abstract

Akt1 is a well-characterized mediator of muscle hypertrophy. In this issue of Cell Metabolism, Izumiya et al. (2008) reveal a striking link between Akt1 signaling, fast muscle fiber size, and whole-body metabolism. These results provide new insights into the ability of muscle to combat diet-induced obesity and metabolic dysfunction.

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