doi: 10.1016/0303-7207(76)90077-0.
The effects of cholera toxin on the adrenal weight in hypophysectomized rats
- PMID: 182572
- DOI: 10.1016/0303-7207(76)90077-0
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The effects of cholera toxin on the adrenal weight in hypophysectomized rats
Mol Cell Endocrinol.
1976 Jun-Jul.
Abstract
The effects of cholera on adrenal weight in hypophysectomized rats were investigated, in an attempt to demonstrate an ACTH-like, adrenal trophic effect of the toxin. The results suggested that the toxin probably exerts is ACTH-like action on the adrenal via adenylate cyclase. Cholera toxin was also shown to have a thermolytic action, similar to that of ACTH, probably due to stimulation of adrenal glucocorticoid secretion.
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