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. 1976 Jun-Jul;5(1-2):147-9.
doi: 10.1016/0303-7207(76)90077-0.

The effects of cholera toxin on the adrenal weight in hypophysectomized rats

J Marton, J W Palfreyman, D Schulster

The effects of cholera toxin on the adrenal weight in hypophysectomized rats

J Marton et al. Mol Cell Endocrinol. 1976 Jun-Jul.

Abstract

The effects of cholera on adrenal weight in hypophysectomized rats were investigated, in an attempt to demonstrate an ACTH-like, adrenal trophic effect of the toxin. The results suggested that the toxin probably exerts is ACTH-like action on the adrenal via adenylate cyclase. Cholera toxin was also shown to have a thermolytic action, similar to that of ACTH, probably due to stimulation of adrenal glucocorticoid secretion.

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