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. 2008 Mar;48(6):773-87.
doi: 10.1016/j.visres.2007.12.007. Epub 2008 Feb 7.

Changes in visual function following optical treatment of astigmatism-related amblyopia

Erin M Harvey  1 , Velma Dobson, Joseph M Miller, Candice E Clifford-Donaldson
Affiliations

Changes in visual function following optical treatment of astigmatism-related amblyopia

Erin M Harvey et al. Vision Res. 2008 Mar.

Abstract

Effects of optical correction on best-corrected grating acuity (vertical (V), horizontal (H), oblique (O)), vernier acuity (V, H, O), contrast sensitivity (1.5, 6.0, and 18.0 cy/deg spatial frequency, V and H), and stereoacuity were evaluated prospectively in 4- to 13-year-old astigmats and a non-astigmatic age-matched control group. Measurements made at baseline (eyeglasses dispensed for astigmats), 6 weeks, and 1 year showed greater improvement in astigmatic than non-astigmatic children for all measures. Treatment effects occurred by 6 weeks, and did not differ by cohort (<8 vs. >or= 8 years), but astigmatic children did not attain normal levels of visual function.

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Figures

Figure 1
Figure 1
A: Mean best-corrected grating acuity at baseline, 6 weeks, and 1 year by astigmatism group (NonA, HA, M/MA) for vertical (triangle symbols), horizontal (square symbols), and oblique (circle symbols) stimuli. Y axis is scaled logarithmically, with 0.1 log unit between tick marks. B: Mean of V-H best-corrected grating acuity at baseline, 6 weeks, and 1 year for by astigmatism group (NonA, HA, M/MA). Bars indicate ± 1 sem.
Figure 2
Figure 2
A: Mean best-corrected vernier acuity at baseline, 6 weeks, and 1 year by astigmatism group (NonA, HA, M/MA) for vertical (triangle symbols), horizontal (square symbols), and oblique (circle symbols) stimuli. Y axis is scaled logarithmically, with 0.1 log unit between tick marks. B: Mean of V-H best-corrected vernier acuity at baseline, 6 weeks, and 1 year for by astigmatism group (NonA, HA, M/MA) Bars indicate ± 1 sem.
Figure 3
Figure 3
Mean best-corrected contrast sensitivity at baseline, 6 weeks, and 1 year by astigmatism group (NonA, HA, M/MA) for vertical (triangle symbols) and horizontal (square symbols) stimuli for A: low spatial frequency (1.5 cy/deg) stimuli. Y axis is scaled logarithmically, with 0.3 log unit between tick marks. B: middle spatial frequency (6.0 cy/deg) stimuli, and C: high spatial frequency (18.0 cy/deg) stimuli. Bars indicate ± 1 sem.
Figure 4
Figure 4
Mean of V-H best-corrected contrast sensitivity at baseline, 6 weeks, and 1 year by astigmatism group (NonA, HA, M/MA) for A: low spatial frequency (1.5 cy/deg) stimuli, B: middle spatial frequency (6.0 cy/deg) stimuli, and C: high spatial frequency (18.0 cy/deg) stimuli. Bars indicate ± 1 sem.
Figure 5
Figure 5
Mean best-corrected stereoacuity at baseline, 6 weeks, and 1 year by astigmatism group (NonA, HA, M/MA). Y axis is scaled logarithmically, with 0.1 log unit between tick marks. Bars indicate ± 1 sem.
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