Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2008 Apr;19(4):399-428.
doi: 10.1007/s00198-008-0560-z. Epub 2008 Feb 12.

European guidance for the diagnosis and management of osteoporosis in postmenopausal women

J A Kanis  1 , N Burlet, C Cooper, P D Delmas, J-Y Reginster, F Borgstrom, R Rizzoli; European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO)
Affiliations
Review

European guidance for the diagnosis and management of osteoporosis in postmenopausal women

J A Kanis et al. Osteoporos Int. 2008 Apr.

Erratum in

  • Osteoporos Int. 2008 Jul;19(7): 1103-4.

Abstract

Guidance is provided in a European setting on the assessment and treatment of postmenopausal women with or at risk from osteoporosis.

Introduction: The European Foundation for Osteoporosis and Bone disease (subsequently the International Osteoporosis Foundation) published guidelines for the diagnosis and management of osteoporosis in 1997. This manuscript updates these in a European setting.

Methods: The following areas are reviewed: the role of bone mineral density measurement for the diagnosis of osteoporosis and assessment of fracture risk; general and pharmacological management of osteoporosis; monitoring of treatment; assessment of fracture risk; case finding strategies; investigation of patients; health economics of treatment.

Results and conclusions: A platform is provided on which specific guidelines can be developed for national use.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Burden of diseases estimated as disability-adjusted life-years (DALYs) lost due to a selection of non-communicable diseases in Europe. (Reprinted from [3], with kind permission from Springer Science + Business Media). IHD ischaemic heart disease, COPD chronic obstructive pulmonary disease, OA osteoarthritis, RA rheumatoid arthritis, BPH benign prostatic hyperplasia
Fig. 2
Fig. 2
Burden of diseases estimated as disability-adjusted life-years (DALYs) lost due to a selection of neoplastic diseases in Europe. (Reprinted from [3], with kind permission from Springer Science + Business Media)
Fig. 3
Fig. 3
Management algorithm in postmenopausal women based on an health economic analysis for the UK. (Adapted from [137])
Fig. 4
Fig. 4
Algorithm for the assessment of fracture probability. (Reprinted from [20], with permission)
Fig. 5
Fig. 5
The effects of glucocorticoid dose on the incidence of fracture. (Reprinted from [131], with kind permission from Springer Science + Business Media)
Fig. 6
Fig. 6
Cost-effectiveness (£000/QALY gained) of treatment in women aged 50–70 years, by the presence or absence of a prior fracture and osteoporosis. (Reprinted from [148], with permission from Elsevier). The solid horizontal line indicates the threshold for cost-effectiveness (£30,000—approximately 43,000 Euros – currency conversion here and elsewhere at October 2007)
See this image and copyright information in PMC

Comment in

References

    1. Consensus Development Conference Diagnosis, prophylaxis and treatment of osteoporosis. Am J Med. 1993;94:646–650. doi: 10.1016/0002-9343(93)90218-E. - DOI - PubMed
    1. Kanis JA, Johnell O, Oden A, Sembo I, Redlund-Johnell I, Dawson A, et al. Long-term risk of osteoporotic fracture in Malmo. Osteoporos Int. 2000;11:669–674. doi: 10.1007/s001980070064. - DOI - PubMed
    1. Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006;17:1726–1733. doi: 10.1007/s00198-006-0172-4. - DOI - PubMed
    1. Kanis JA, Johnell O, on behalf of the Committee of Scientific Advisors of the International Osteoporosis Foundation Requirements for DXA for the management of osteoporosis in Europe. Osteoporos Int. 2005;16:220–238. - PubMed
    1. Cooper C, Atkinson EJ, Jacobsen SJ, O’Fallon WM, Melton LJ. A population based study of survival after osteoporotic fractures. Am J Epidemiol. 1993;137:1001–1005. - PubMed