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. 1976 Sep;127(3):1590-2.
doi: 10.1128/jb.127.3.1590-1592.1976.

Growth inhibition of Proteus mirabilis by cyclic adenosine 3'-5'-monophosphate

R H Schwarzhoff, F D Williams

Growth inhibition of Proteus mirabilis by cyclic adenosine 3'-5'-monophosphate

R H Schwarzhoff et al. J Bacteriol. 1976 Sep.

Abstract

Growth of Proteus mirabilis on a synthetic agar medium containing either glycerol, galactose, or trehalose as the sole source is inhibited by 5 mM cyclic adenosine 3',5'-monophosphate (cAMP). Inhibition on an agar medium is evident as loss of viability, but in broth cAMP only slightly inhibits growth rate. Inhibition is associated with the accumulation of methylglyoxal in the medium. A nonswarming mutant of P. mirabilis is not inhibited by cAMP on either of the three carbon sources, but it is sensitive to exogenous methylglyoxal.

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References

    1. J Bacteriol. 1975 Oct;124(1):567-9 - PubMed
    1. J Bacteriol. 1974 Aug;119(2):357-62 - PubMed
    1. J Bacteriol. 1971 Oct;108(1):137-44 - PubMed
    1. J Bacteriol. 1976 Jul;127(1):237-48 - PubMed

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