Animal models of renal disease
- PMID: 18274542
- DOI: 10.1038/sj.ki.5002724
Animal models of renal disease
Abstract
Mice have become a favored species to model disease. Many mouse strains have proven relatively resistant to some manipulations that have generated renal disease in other species. Kirchhoff et al. describe a means of producing hypertension, proteinuria, and glomerular sclerosis in a mouse strain.
Comment on
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Rapid development of severe end-organ damage in C57BL/6 mice by combining DOCA salt and angiotensin II.Kidney Int. 2008 Mar;73(5):643-50. doi: 10.1038/sj.ki.5002689. Epub 2007 Nov 21. Kidney Int. 2008. PMID: 18033241
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