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Case Reports
. 2008 Mar;105(3):e76-9.
doi: 10.1016/j.tripleo.2007.10.001.

Giant mature ovarian cystic teratoma including more than 300 teeth

Laurent Devoize  1 , Denise Collangettes, Guillaume Le Bouëdec, Florence Mishellany, Thierry Orliaguet, Radhouane Dallel, Martine Baudet-Pommel
Affiliations
Case Reports

Giant mature ovarian cystic teratoma including more than 300 teeth

Laurent Devoize et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Mar.

Abstract

Preoperative diagnosis of malignant tumors arising from mature cystic teratoma (MCT) of the ovary is not easy; malignant tumors are mostly diagnosed only postoperatively. Tumor size, serum tumor markers, and patient age have been proposed as risk factors for malignancy. This article reports a rare case of a giant, benign MCT of the ovary in a young woman (25 years old). It had a very large size (320 x 270 x 185 mm, 10 kg), a great number of teeth (> 300), and preoperative serum level of tumor markers were elevated (CA125, 875 U/mL(-1); CA19-9, 2087 U/mL(-1); CEA, 5.1 ng/mL(-1); AFP, 23.3 ng/mL(-1); SCC, 20.7 ng/mL(-1)). Based on clinical and laboratory data, tumor markers and tumor size when used alone or in combination do not appear to be useful in making a differential diagnosis between MCT and squamous cell carcinoma arising from MCT. However, radiologically detectable, well-differentiated teeth may be indicative of benignity.

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