doi: 10.1016/0014-5793(91)80605-3.
Evidence for a role of phosphofructokinase and tRNA in the polyribosome disaggregation of amino acid deficiency
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- PMID: 1828439
- DOI: 10.1016/0014-5793(91)80605-3
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Evidence for a role of phosphofructokinase and tRNA in the polyribosome disaggregation of amino acid deficiency
FEBS Lett.
.
Free article
Abstract
The activity of rabbit muscle phosphofructokinase was inhibited by transfer ribonucleic acid. This inhibition was reduced by inclusion of an amino-acyl-tRNA charging system. The results are discussed in terms of the loss of ATP in amino acid deprived cells and in the critical role of fructose 1,6-diphosphate in peptide chain initiation.
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