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. 1991 Jun 3;283(2):270-2.
doi: 10.1016/0014-5793(91)80605-3.

Evidence for a role of phosphofructokinase and tRNA in the polyribosome disaggregation of amino acid deficiency

M Rabinovitz  1
Affiliations
Free article

Evidence for a role of phosphofructokinase and tRNA in the polyribosome disaggregation of amino acid deficiency

M Rabinovitz. FEBS Lett. .
Free article

Abstract

The activity of rabbit muscle phosphofructokinase was inhibited by transfer ribonucleic acid. This inhibition was reduced by inclusion of an amino-acyl-tRNA charging system. The results are discussed in terms of the loss of ATP in amino acid deprived cells and in the critical role of fructose 1,6-diphosphate in peptide chain initiation.

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