Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2008 Aug;19(8):878.
doi: 10.1111/j.1540-8167.2007.01075.x. Epub 2008 Feb 13.

Placebo CRT

Niraj Varma  1 , Ping Jia, Yoram Rudy
Affiliations
Case Reports

Placebo CRT

Niraj Varma et al. J Cardiovasc Electrophysiol. 2008 Aug.
No abstract available

PubMed Disclaimer

Figures

Figure
Figure
The figure depicts an ECGI-constructed epicardial isochrone map during simultaneous biventricular pacing (CRT). Epicardial surfaces of both ventricles are displayed in three views: anterior, left lateral, and posterior. There is overlap between adjacent views. The left anterior descending (LAD) coronary artery is marked. Selected ECGI-reconstructed epicardial electrograms are indicated by arrows. Pacing sites (RV and LV, asterisks), as expected, are the earliest ventricular sites to be activated (red). Thereafter, LV activation is irregular with development of regions of conduction block (thick black markings) and slowing (crowded isochrones) displaying fractionated local electrograms. These delay activation of a large territory of the lateral/posterolateral LV. In fact, this region is activated terminally (blue) despite pacing from an immediately adjacent site. Electrograms are preserved in this area indicating epicardial viability. Hence, LV pacing failed to achieve target area preexcitation.
See this image and copyright information in PMC

References

    1. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, Tavazzi L. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005;352:1539–49. - PubMed
    1. Ramanathan C, Ghanem RN, Jia P, Ryu K, Rudy Y. Noninvasive electrocardiographic imaging for cardiac electrophysiology and arrhythmia. Nat Med. 2004;10:422–428. - PMC - PubMed

Publication types

MeSH terms