Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2008 Apr;51(4):e22-3.
doi: 10.1161/HYPERTENSIONAHA.107.109454. Epub 2008 Feb 19.

Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study

Ana Luiza Maia, Shih-Jen Hwang, Daniel Levy, Martin G Larson, P Reed Larsen, Caroline S Fox
Comment

Lack of association between the type 2 deiodinase A/G polymorphism and hypertensive traits: the Framingham Heart Study

Ana Luiza Maia et al. Hypertension. 2008 Apr.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Mentuccia D, Proietti-Pannunzi L, Tanner K, Bacci V, Pollin TI, Poehlman ET, Shuldiner AR, Celi FS. Association between a novel variant of the human type 2 deiodinase gene Thr92Ala and insulin resistance: evidence of interaction with the Trp64Arg variant of the beta-3-adrenergic receptor. Diabetes. 2002;51:880–3. - PubMed
    1. Canani LH, Capp C, Dora JM, Meyer EL, Wagner MS, Harney JW, Larsen PR, Gross JL, Bianco AC, Maia AL. The Type 2 Deiodinase A/G (Thr92Ala) Polymorphism is associated with Decreased Enzyme Velocity and Increased Insulin Resistance in Patients with Type 2 Diabetes Mellitus. Journal of Clinical Endocrinology and Metabolism. 2005;90:3472–8. - PubMed
    1. Maia AL, Dupuis J, Manning A, Liu C, Meigs JB, Cupples LA, Larsen PR, Fox CS. The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study. Thyroid. 2007;17:199–202. - PubMed
    1. Grarup N, Andersen MK, Andreasen CH, Albrechtsen A, Borch-Johnsen K, Jorgensen T, Auwerx J, Schmitz O, Hansen T, Pedersen O. Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects. J Clin Endocrinol Metab. 2007;92:363–6. - PubMed
    1. Gumieniak O, Perlstein TS, Williams JS, Hopkins PN, Brown NJ, Raby BA, Williams GH. Ala92 type 2 deiodinase allele increases risk for the development of hypertension. Hypertension. 2007;49:461–6. - PubMed

Substances