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Review
. 2008 Feb;8(2):97-106.
doi: 10.2174/138955708783498131.

Interactions of polyphenols with the P450 system: possible implications on human therapeutics

I Rodeiro  1 , M T Donato, A Lahoz, G Garrido, R Delgado, M J Gómez-Lechón
Affiliations
Review

Interactions of polyphenols with the P450 system: possible implications on human therapeutics

I Rodeiro et al. Mini Rev Med Chem. 2008 Feb.

Abstract

Polyphenols are a family of natural compounds with many biological properties. This review focuses on their potential interaction on the cytochrome P450 system. Effects of phenolic acids, anthocyanins, stilbenes, catechins and other flavonoids on the drug metabolising function are revised. Their daily intake and presence in herbal medicines justify the study of potential drug-interaction to prevent undesirable clinical consequences.

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