Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 May;52(5):1888-90.
doi: 10.1128/AAC.00035-08. Epub 2008 Feb 25.

Emergence of fluoroquinolone resistance in group B streptococcal isolates in Taiwan

Affiliations

Emergence of fluoroquinolone resistance in group B streptococcal isolates in Taiwan

Hsiu-Mei Wu et al. Antimicrob Agents Chemother. 2008 May.

Abstract

Of 1,994 group B streptococcal isolates collected, 26 (1.3%) of the isolates were resistant to levofloxacin, and cross-resistance to other fluoroquinolones was observed. The emergence and prevalence of high-level fluoroquinolone resistance in genetically unrelated isolates were linked to the presence of gyrA, parC, and parE triple mutations in each isolate.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
PFGE patterns of 26 fluoroquinolone-resistant GBS isolates. The designations for isolates that were represented by each pulse type are shown below the gels. Lanes M contain a lambda ladder (Gibco) that served as a molecular marker.

References

    1. Biedenbach, D. J., M. A. Toleman, T. R. Walsh, and R. N. Jones. 2006. Characterization of fluoroquinolone-resistant beta-hemolytic Streptococcus spp. isolated in North America and Europe including the first report of fluoroquinolone-resistant Streptococcus dysgalactiae subspecies equisimilis: report from the SENTRY Antimicrobial Surveillance Program (1997-2004). Diagn. Microbiol. Infect. Dis. 55:119-127. - PubMed
    1. Clinical and Laboratory Standards Institute. 2006. Performance standards for antimicrobial disk susceptibility tests, 9th ed. Approved standard M2-A9. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. Clinical and Laboratory Standards Institute. 2006. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 7th ed. Approved standard M7-A7. Clinical and Laboratory Standards Institute, Wayne, PA.
    1. González, I., M. Georgiou, F. Alcaide, D. Balas, J. Liñares, and A. G. de la Campa. 1998. Fluoroquinolone resistance mutations in the parC, parE, and gyrA genes of clinical isolates of viridans group streptococci. Antimicrob. Agents Chemother. 42:2792-2798. - PMC - PubMed
    1. Hooper, D. C. 2002. Fluoroquinolone resistance among Gram-positive cocci. Lancet Infect. Dis. 2:530-538. - PubMed

Publication types

MeSH terms

LinkOut - more resources