Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2008 Feb 19;22(4):540-1.
doi: 10.1097/QAD.0b013e3282f37812.

HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

Zulma G Vitezica  1 , Brigitte Milpied, Christine Lonjou, Nicolas Borot, Terence Niel Ledger, Anne Lefebvre, Alain Hovnanian
Affiliations
Multicenter Study

HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz

Zulma G Vitezica et al. AIDS. .

Abstract

HLA typing, demographic and immunological risk factors for nevirapine and efavirenz reactions were studied in a French cohort of HIV patients. Cases with isolated rash were significantly associated with HLA-DRB101 allele. No liver toxicity was observed and no association was detected with the percentage of CD4 T-cells. This study suggests that HLA-DRB101 allele plays an important role in susceptibility to cutaneous reactions associated with nevirapine and efavirenz in HIV patients.

PubMed Disclaimer

Publication types