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Review
. 2008 Feb;5(2):e55.
doi: 10.1371/journal.pmed.0050055.

Eliminating human African trypanosomiasis: where do we stand and what comes next?

Pere P Simarro  1 , Jean Jannin, Pierre Cattand
Affiliations
Review

Eliminating human African trypanosomiasis: where do we stand and what comes next?

Pere P Simarro et al. PLoS Med. 2008 Feb.

Abstract

While the number of new detected cases of HAT is falling, say the authors, sleeping sickness could suffer the "punishment of success," receiving lower priority by public and private health institutions.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. New Cases of Sleeping Sickness Reported for All Africa between 1927 and 1997
Figure 2
Figure 2. HAT Transmission Cycle
In T. b. gambiense the cycle is mostly human-to-human (central circle); occasionally transmission may occur from animal to human. In T. b. rhodesiense the animal reservoir plays an important role in the cycle, thus sustaining parasite transmission and human infections.
Figure 3
Figure 3. Map of Africa Showing the Epidemiological Status of Countries Considered Endemic for the Disease
Figure 4
Figure 4. T. b. gambiense: Comparative Evolution Curves between Population Placed Under Active Surveillance and New Cases Reported (1997–2006)
See this image and copyright information in PMC

References

    1. World Health Organization. Resolution 50.36, 50th World Health Assembly. Geneva: World Health Organization; 1997.
    1. Chappuis F, Loutan L, Simarro P, Lejon V, Büscher P. Options for field diagnosis of human African trypanosomiasis. Clin Microbiol Rev. 2005;18:133–146. - PMC - PubMed
    1. World Health Organization. Human African trypanosomiasis (sleeping sickness): Epidemiological update. Wkly Epidemiol Rec. 2006;8:71–80. Available: http://www.who.int/wer/2006/wer8108/en/index.html. Accessed 21 January 2008. - PubMed
    1. World Health Organization. WHO programme to eliminate sleeping sickness—Building a global alliance. 2002. Available: http://whqlibdoc.who.int/hq/2002/WHO_CDS_CSR_EPH_2002.13.pdf. Accessed 21 January 2008.
    1. Food and Agriculture Organization, Animal Production and Health Division. Programme Against African Trypanosomiasis. 2008. Available: http://www.fao.org/PAAT/html/home.htm. Accessed 21 January 2008.

MeSH terms