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. 2008 Feb;6(2):e52.
doi: 10.1371/journal.pbio.0060052.

Does mutation rate depend on itself

Charles F Baer  1
Affiliations

Does mutation rate depend on itself

Charles F Baer. PLoS Biol. 2008 Feb.

Abstract

Recent evidence suggests that mutation rates are fitness-dependent, broadening our view of the impacts of mutation on the genetic health of populations.

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Figures

Figure 1
Figure 1. Graph of Mutation Rate (U) against Mutation Load
Plot of U as a function of mutation load, scaled relative to that of the least-loaded genotype (U MIN = 0). Ui = U MAX− (U MAX −U MIN) Wi k. Load = 1 − wi where wi is relative fitness of a genotype with i deleterious mutations; wmax = w 0 = 1. Note: this figure is slightly different from the analogous figure in [10] in which mutation rate is plotted against fitness rather than load.
See this image and copyright information in PMC

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