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Review
. 2008;9(2):208.
doi: 10.1186/gb-2008-9-2-208. Epub 2008 Feb 19.

Intron mis-splicing: no alternative?

Scott William Roy  1 , Manuel Irimia
Affiliations
Review

Intron mis-splicing: no alternative?

Scott William Roy et al. Genome Biol. 2008.

Abstract

A recent report reveals widespread mis-splicing of RNA transcripts in eukaryotes, with mis-spliced RNA destroyed by nonsense-mediated mRNA decay. This striking inefficiency deepens the mystery of the proliferation and persistence of introns.

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