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. 2008 Apr 24;70(6):1104-8.
doi: 10.1016/j.jprot.2007.12.008. Epub 2008 Jan 7.

Cyanine dyes for the detection of double stranded DNA

H Hilal  1 , J A Taylor
Affiliations

Cyanine dyes for the detection of double stranded DNA

H Hilal et al. J Biochem Biophys Methods. .

Abstract

Twenty three novel cyanine dyes have been applied as fluorescent stains for the detection of nucleic acids in agarose gel electrophoresis. Significant fluorescence enhancement of these dyes in the presence of double stranded DNA was observed. Five dyes offered superior sensitivity in the detection and quantification of DNA, over Ethidium Bromide, the most commonly used nucleic acid stain.

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