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. 2008 Apr 7;343(5):977-81.
doi: 10.1016/j.carres.2008.02.002. Epub 2008 Feb 10.

The O-polysaccharide of Escherichia coli O112ac has the same structure as that of Shigella dysenteriae type 2 but is devoid of O-acetylation: a revision of the S. dysenteriae type 2 O-polysaccharide structure

Andrei V Perepelov  1 , Andrej Weintraub, Bin Liu, Sof'ya N Senchenkova, Alexander S Shashkov, Lu Feng, Lei Wang, Göran Widmalm, Yuriy A Knirel
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The O-polysaccharide of Escherichia coli O112ac has the same structure as that of Shigella dysenteriae type 2 but is devoid of O-acetylation: a revision of the S. dysenteriae type 2 O-polysaccharide structure

Andrei V Perepelov et al. Carbohydr Res. .

Abstract

The O-antigen structure of Shigella dysenteriae type 2 was reinvestigated using chemical modifications along with high-resolution 2D (1)H and (13)C NMR spectroscopy. The O-antigen was found to contain a pyruvic acid acetal, which was overlooked in an early study, and the following revised structure of the pentasaccharide repeating unit was established: where approximately 70% GlcNAc residues bear an O-acetyl group at position 3. The O-antigen of Escherichia coli O112ac was found to have the same carbohydrate structure but to lack O-acetylation.

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