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Editorial
. 2008 Mar 22;336(7645):623-4.
doi: 10.1136/bmj.39497.622720.80. Epub 2008 Feb 29.

Managing uninvestigated dyspepsia in primary care

Naoki Chiba
Editorial

Managing uninvestigated dyspepsia in primary care

Naoki Chiba. BMJ. .

Abstract

Test and treat for Helicobacter pylori is still as good as proton pump inhibitors first

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Conflict of interest statement

Competing interests: NC has received honoraria from Abbott, Astra-Zeneca, Janssen, and Nycomed for giving talks about proton pump inhibitor and dyspepsia. NC has also received research support from Astra-Zeneca.

Comment on

References

    1. Delaney BC, Qume M, Moayyedi P, Logan RFA, Ford AC, Elliott C, et al. Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial). BMJ 2008. doi: 10.1136/bmj.39479.640486.AE - DOI - PMC - PubMed
    1. Chiba N, Veldhuyzen van Zanten SJO, Sinclair P, Ferguson RA, Escobedo S, Grace E. Treatment of H pylori infection in primary care patients with uninvestigated dyspepsia improves symptoms: the CADET-Hp (Canadian adult dyspepsia empiric treatment-Helicobacter pylori positive) randomised controlled trial. BMJ 2001;324:1012-6. - PMC - PubMed
    1. Veldhuyzen van Zanten SJ, Chiba N, Armstrong D, Barkun A, Thomson A, Smyth S, et al. A randomized trial comparing omeprazole, ranitidine, cisapride, or placebo in Helicobacter pylori negative, primary care patients with dyspepsia: The CADET-HN study. Am J Gastroenterol 2005;100:1477-88. - PubMed
    1. Veldhuyzen van Zanten SJ, Flook N, Chiba N, Armstrong D, Barkun A, Bradette M, et al. An evidence-based approach to the management of uninvestigated dyspepsia in the era of Helicobacter pylori. Canadian Dyspepsia Working Group. CMAJ 2000;162(suppl 12):S3-23. - PMC - PubMed
    1. Armstrong D, Veldhuyzen van Zanten SJ, Barkun AN, Chiba N, Thomson AB, Smyth S, et al. Heartburn-dominant, uninvestigated dyspepsia: a comparison of “PPI-start” and “H2-RA-start” management strategies in primary care—the CADET-HR study. Aliment Pharmacol Ther 2005;21:1189-202. - PubMed

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