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Clinical Trial
. 2008 Mar;93(3):471-2.
doi: 10.3324/haematol.12013.

Investigation of FDG-PET/CT imaging to guide biopsies in the detection of histological transformation of indolent lymphoma

Caroline Bodet-Milin, Françoise Kraeber-Bodéré, Philippe Moreau, Loïc Campion, Benoît Dupas, Steven Le Gouill
Free article
Clinical Trial

Investigation of FDG-PET/CT imaging to guide biopsies in the detection of histological transformation of indolent lymphoma

Caroline Bodet-Milin et al. Haematologica. 2008 Mar.
Free article

Abstract

Positron emission tomography using 18F-fluorodeoxyglucose (FDG-PET) has been successfully evaluated in the management of non-Hodgkin's lymphoma (NHL).1-3 Histological transformation (HT) of indolent lymphoma is a dramatic event that occurs in 5-10% of the patients and carries a dismal prognosis.4,5 Previous studies prove that indolent lymphoma entities show a lower FDG uptake when compared with aggressive lymphomas.6-8 We therefore postulated that FDG-PET/CT identifies aggressive transformation sites and can guide biopsies.

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