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Review
. 1991 Aug;38(4):889-903.
doi: 10.1016/s0031-3955(16)38158-5.

Acne vulgaris. Pathogenesis and treatment

M H Winston  1 , A R Shalita
Affiliations
Review

Acne vulgaris. Pathogenesis and treatment

M H Winston et al. Pediatr Clin North Am. 1991 Aug.

Abstract

Acne vulgaris is a multifactorial disease involving abnormalities in follicular keratinization, sebum production, proliferation of Propionibacterium acnes, and inflammation. Treatment is directed toward reversing these underlying pathogenic factors. Therapeutic options include topical comedolytics, topical and systemic antibiotics, hormonal manipulations, and oral retinoids.

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