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. 1991 Aug 27;1090(1):1-8.
doi: 10.1016/0167-4781(91)90029-l.

Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping

S Tominaga  1 , N A Jenkins, D J Gilbert, N G Copeland, T Tetsuka
Affiliations

Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping

S Tominaga et al. Biochim Biophys Acta. .

Abstract

The genomic locus of the murine ST2 gene was isolated based on homology with a murine ST2 complementary DNA sequence and its complete nucleotide sequence was determined. The locus is composed of eight exons and seven introns and is approx. 9 kilobase pairs in size. Two Sp1 binding sites are present in the 5' flanking region. The murine ST2 gene, which was expressed only in the growth-stimulated BALB/c-3T3 cells, was mapped to mouse chromosome one, very tightly linked to the interleukin 1 receptor-type 1 locus.

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