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. 2008 Mar 26;130(12):3736-7.
doi: 10.1021/ja710990d. Epub 2008 Mar 6.

Fluorenes and styrenes by Au(I)-catalyzed annulation of enynes and alkynes

David J Gorin  1 , Iain D G Watson, F Dean Toste
Affiliations

Fluorenes and styrenes by Au(I)-catalyzed annulation of enynes and alkynes

David J Gorin et al. J Am Chem Soc. .

Abstract

Intermolecular annulation of enynes and propargyl esters to selectively produce styrenes or fluorenes is reported. The divergent arene syntheses involve a Au-catalyzed, two-pot, multistep process proceeding by cis-diastereoselective cyclopropanation, cycloisomerization, and, finally, annulation or elimination.

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Figures

Scheme 1
Scheme 1
Proposed Mechanism for the Formation of 3 and 4.
See this image and copyright information in PMC

References

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