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. 2008 Apr;9(4):322-6.
doi: 10.1038/embor.2008.30. Epub 2008 Mar 7.

The physiology and pathology of the EMT. Meeting on the epithelial-mesenchymal transition

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The physiology and pathology of the EMT. Meeting on the epithelial-mesenchymal transition

Hervé Acloque et al. EMBO Rep. 2008 Apr.
No abstract available

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Figures

Figure 1
Figure 1
The epithelial–mesenchymal transition in cancer: past, present and future perspectives. Betty Hay coined the term epithelial-to-mesenchymal transformation some 40 years ago and left us beautiful drawings that not only show the transformation to mesenchyme, but also the transient nature of the process and the reversion to the epithelial character (MET; Hay, 1968, 1995). This is why the preferred term is now epithelial-to-mesenchymal transition (EMT). The EMT, as an initial step in the metastatic cascade, has until recently remained a matter of debate; however, powerful imaging tools have convincingly shown that individual cells delaminate from primary tumours (Condeelis & Segall, 2003). Bv, blood vessels; ECM, extracellular matrix; Lv, lymphatic vessels.
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From left: Jean Paul Thiery, M. Angela Nieto & Hervé Acloque
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The third international symposium on the Epithelial–Mesenchymal Transition was an EMBO workshop organized by TEMTIA (The International EMT Organization) and the European network EpiPlastCarcinoma. It took place between 10 and 12 September 2007, at the Larisha Palace in Krakow, Poland, and was organized by P. Savagner, A. Moustakas, A. Garcia de Herreros and A. Cano.

References

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