Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2008 Mar;14(3):390-6.
doi: 10.3201/eid1403.061143.

Epidemiology of nontuberculous mycobacteria in patients without HIV infection, New York City

Ethan E Bodle  1 , Jennifer A Cunningham, Phyllis Della-Latta, Neil W Schluger, Lisa Saiman
Affiliations

Epidemiology of nontuberculous mycobacteria in patients without HIV infection, New York City

Ethan E Bodle et al. Emerg Infect Dis. 2008 Mar.

Abstract

We reviewed medical records of patients without known HIV and with positive cultures for nontuberculous mycobacteria (NTM) isolated during 2000-2003 from 1 large hospital in New York, New York. Overall, 505 patients had positive NTM cultures; 119 (24%) met the criteria for NTM disease. The difference between demographic characteristics of case-patients in our study (66% female, 61% white, and 59% > 60 years of age) and those of the base population as determined by regional census data was statistically significant. Estimated incidences for positive cultures, all disease, and respiratory tract disease were 17.7, 2.7, and 2.0 per 100,000 persons, respectively. More patients with rapidly growing mycobacteria (61%), Mycobacterium kansasii (70%), or M. marinum (100%) met criteria for disease than did patients with M. avium complex (MAC) (27%, (p < 0.01). NTM disease in patients without HIV is increasing. Laboratory-based surveillance may be useful for detecting non-MAC and non-respiratory tract disease.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Flowchart of patient selection for cases of nontuberculous mycobacteria (NTM) colonization and NTM disease among patients without HIV infection, New York–Presbyterian Hospital (NYPH), Columbia University Medical Center, 2000–2003.
Figure 2
Figure 2
Distribution by sex of patients with positive nontuberculous mycobacteria (NTM) cultures, NTM disease, and disease of the respiratory tract caused by Mycobacterium avium complex (MAC), New York–Presbyterian Hospital, Columbia University Medical Center, 2000–2003, compared with age-adjusted base population from 2000 US Census data.
Figure 3
Figure 3
Distribution by race of patients with positive nontuberculous mycobacteria (NTM) cultures, NTM disease, and disease of the respiratory tract caused by Mycobacterium avium complex (MAC), New York–Presbyterian Hospital, Columbia University Medical Center, 2000–2003, compared with age-adjusted base population from 2000 US Census data.
See this image and copyright information in PMC

References

    1. Falkinham JO. Epidemiology of nontuberculous mycobacteria. Clin Microbiol Rev. 1996;9:177–215. - PMC - PubMed
    1. Wolinsky E. Nontuberculous mycobacteria and associated diseases. Am Rev Respir Dis. 1979;119:107–59. - PubMed
    1. O'Brien RJ, Geiter LJ, Snider DE Jr. The epidemiology of nontuberculous mycobacterial diseases in the United States. Results from a national survey. Am Rev Respir Dis. 1987;135:1007–14. - PubMed
    1. Ahn CH, Lowell JR, Onstad GD, Shuford EH, Hurst GA. A demographic study of disease due to Mycobacterium kansasii or M. intracellulare-avium in Texas. Chest. 1979;75:120–5. 10.1378/chest.75.2.120 - DOI - PubMed
    1. Butler W, Crawford J, Shutt K. Nontuberculous mycobacteria reported to the Public Health Laboratory Information System by state public health laboratories, United States, 1993–1996. Atlanta: Centers for Disease Control and Prevention; 1999.

MeSH terms